In the UK, Chiltern's own Clinical Research Unit carries out a number of clinical studies.
New treatments are continually being developed for the treatment of disease. However, it is a complex process with many stages of development before a new medicine can be used to treat patients. A promising new drug must be extensively investigated before it is thought to be safe to be given to humans. It is then tested in healthy volunteers so that certain properties of the drug can be determined.
For example, it might be necessary to find out:
- how long a drug stays in the body
- the drug has the desired effect
- whether the drug has any other effects e.g. on blood pressure, pulse etc.
- how the drug interacts with other drugs
This type of information will help to determine:
- the optimum dosage
- how often the drug needs to be taken
- the optimum method of administration
- the interaction with other drugs
- which patients may have potential problems with the drug
During any drug trial patient safety and good clinical practice are our primary concern. All volunteers are seen by one of our medical doctors to check they are suitable for the trial. As part of the screening procedure and during the clinical trial the following are usually assessed:
- heart rate (including ECGs)
- blood pressure
- blood and urine samples
Often volunteers are required to stay in out unit for a few days and will be compensated for this.
Safety and restrictions:
All studies undertaken are conduction in as safe a manner as possible and continually monitored. An Independent Ethical Research Committee reviews a proposed clinical trial to ensure that the highest possible safety standards are maintained to protect the rights, safety and well-being of the volunteers. A clinical study cannot take place unless it has been passed by the Ethics Research Committee. As well as the trial being discussed by our own medical doctors, other medical specialists are consulted prior to any volunteers participating in a study. All volunteers are given a written information sheet before they are asked to give informed consent. All volunteers are free to withdraw from the trial at any time without detriment to their medical care.
Study Restrictions:
These might include not smoking or drinking alcohol, avoiding certain foods, or restraining from strenuous physical exercise. Volunteers will be given a list of specific restrictions before entering a study.
The Uniquely Qualified Staff Include:
- On site full-time medical doctors
- Experienced registered nurses and technicians
- Recruitment team and Administrative staff
Contact Recruitment - 0800 783 0976
